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Timothy J. Garrett Laboratory - Department of Pathology, Immunology and Laboratory Medicine

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Ontogeny and function of murine epidermal Langerhans cells

Kaplan reviews the development of skin-resident Langerhans cells and their unique functional roles that distinguish these cells from other skin antigen-presenting cells.

IFN-λ 'guts' neutrophil-mediated inflammation

Interferon-λ (IFN-λ) curbs neutrophil-mediated intestinal inflammation by diminishing the production of reactive oxygen species and subsequent oxidative stress. This regulatory process is unique to...

(T)Betting on innate lymphoid cells in CNS inflammatory disease

T-bet+NKp46+ subsets of group 1 and group 3 innate lymphoid cells within the meninges initiate neuroinflammation in central nervous system (CNS)-demyelinating disease by regulating both the stability...

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