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David A. Ostrov Laboratory - Department of Pathology, Immunology & Laboratory Medicine

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Regulatory ILCs

September 19, 2017

Ontogeny and function of murine epidermal Langerhans cells

September 19, 2017

Kaplan reviews the development of skin-resident Langerhans cells and their unique functional roles that distinguish these cells from other skin antigen-presenting cells.

IFN-λ 'guts' neutrophil-mediated inflammation

September 19, 2017

Interferon-λ (IFN-λ) curbs neutrophil-mediated intestinal inflammation by diminishing the production of reactive oxygen species and subsequent oxidative stress. This regulatory process is unique to...

Blood TFR cells

September 19, 2017

(T)Betting on innate lymphoid cells in CNS inflammatory disease

September 19, 2017

T-bet+NKp46+ subsets of group 1 and group 3 innate lymphoid cells within the meninges initiate neuroinflammation in central nervous system (CNS)-demyelinating disease by regulating both the stability...


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