Northeastern University

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Chemical Engineering

Edgar D. Goluch

DiPietro Assistant Professor
Department of Chemical Engineering

Office: 459 SN
Phone: 617.373-3500
e.goluch@neu.edu
Goluch Group

Education:

  • B.S. (Chemical Engineering) University of Illinois at Urbana-Champaign, 2003
  • M.S. (Mechanical Engineering) University of Illinois at Urbana-Champaign, 2005
  • Ph.D. (Bioengineering) University of Illinois at Urbana-Champaign, 2007
  • N.S.F. Postdoctoral Fellow Delft University of Technology, NL, 2008-2010

Expertise:

  • Biochemistry
  • Biophysics
  • Microfluidics
  • Nanotechnology

Research Focus/Background:

The primary focus of our research is the development of detection strategies that are tailored for the micro and nanoscale, with emphasis on biological systems. We work at size scales ranging from single molecules to single cells. Applications of this research range from personalized medicine to environmental monitoring. We also have expertise in electrochemistry and fabrication of integrated microfluidic systems.

Selected Publications:

  • "Up-Regulating pyocyanin production by amino acid addition for early electrochemical identification of Pseudomonas aeruginosa," Sismaet, H.J., Webster, T.A., Goluch, E.D. Analyst 2014, 139, 4241-4246.
  • "Isolation of microorganisms using sub-micrometer constrictions," Tandogan, N., Abadian, P.N., Epstein, S., Aoi, Y., Goluch, E.D., PLoS ONE 2014, 9(6), e101429.
  • "Using surface plasmon resonance imaging (SPRi) to study bacterial biofilms," Abadian, P.N., Tandogan, N., Jamieson, J.J., Goluch, E.D., Biomicrofluidics 2014, 8, 021804.
  • "Electrochemical detection of pyocyanin in nanochannels with integrated palladium hydride reference electrodes" Webster, T.A., Goluch, E.D., Lab-on-a-Chip 2012, 12, 5195-5201.
  • "Redox cycling in nanofluidic channels using interdigitated electrodes," Goluch, E.D., Wolfrum, B., Singh, P.S., Zevenbergen, M.A.G., Lemay, S.G. Analytical and Bioanalytical Chemistry 394, 447 (2009).
  • "Electrochemical correlation spectroscopy in nanofluidic cavities," Zevenbergen,M.A.G., Singh, P.S., Goluch, E.D., Wolfrum, B.L., Lemay, S.G. Analytical Chemistry 81, 8203 (2009).
  • "A microfluidic detection system based upon a surface immobilized biobarcode assay," Goluch, E.D., Stoeva, S.I., Lee, J.-S., Shaikh, K.A., Mirkin, C.A., Liu, C. Biosensors and Bioelectronics 24, 2397 (2009).
  • "Microfluidic patterning of Nanodisc lipid bilayers and multiplexed analysis of protein interaction," Goluch, E.D., Shaw, A.W., Sligar, S., Liu, C. Lab-on-a-Chip 8, 1723 (2008).
  • "A bio-barcode assay for on-chip attomolar-sensitivity protein detection," Goluch, E.D., Nam, J.M., Georganopoulou, D.G., Chiesl, T.N. Shaikh, K.A., Ryu, K.S., Barron, A.E., Mirkin, C.A., Liu, C. Lab-on-a-Chip 6, 1293 (2006).

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