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Biological Safety


Biosafety Guidelines for CRISPR-cas Research

All research projects involving the CRISPR-cas genome editing technology must be registered with the UF Biosafety Office and reviewed by the Institutional Biosafety Committee (IBC).  The link to the registration forms is

Visit the Biosafety Guidelines for CRISPR-cas Research pages for:

Questions required to conduct proper risk assessment and corresponding mitigation procedures, such as:

Risk Assessment Questions

Risk Mitigation

Will the research be done in bacteria, cell cultures, plants, insects, or whole animals?

Using human-derived cell lines will require BSL-2 practices.  Use in animals will require IACUC approval. Use in plants or insects will require specific containment.

Top 12 Tips to Address Biosafety Concerns can be found here:





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