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Biographical Sketch: DAVID C. FORBES

ADDRESS AND NUMBERS
Department of Chemistry, CHEM 223,
University of South Alabama,
Mobile, AL 36688 Phone: (251) 460-6181
Fax: (251) 460-7359
email address: dforbes@southalabama.edu
PROFESSIONAL PREPARATION

Bachelor of Science, Chemistry, May 1989, University of Florida (Professor Eric Enholm)
Doctor of Philosophy, Chemistry, February 1996, University of Illinois (Professor Scott Denmark)
Postdoctoral Research Associate, Chemistry, July 1997, Trinity University (Professor Michael Doyle)
Postdoctoral Research Associate, Chemistry, July 1998, University of Arizona (Prof. Michael Doyle)

ACADEMIC APPOINTMENTS

Assistant Professor, Department of Chemistry, University of South Alabama.  August 1998 – August 2004.
Associate Professor, Department of Chemistry, University of South Alabama.  August 2004 – August 2008.
Professor, Department of Chemistry, University of South Alabama.  August 2008 – present.

PROFESSIONAL APPOINTMENTS

Assistant Director, University Honors Program, University of South Alabama.  January 2003 – January 2009.
Interim Chair, Department of Chemistry, University of South Alabama.  January 2009 – January 2010.
Associate Graduate Faculty Status, Department of Chemistry, University of South Alabama.  January 2006 – December 2008.
Interim Graduate Coordinator, Environmental Toxicology, University of South Alabama.  December 2009 – August 2010.
Full Graduate Faculty Status, Department of Chemistry, University of South Alabama.  January 2010 – December 2015.
Chair, Department of Chemistry, University of South Alabama.  May 2010 – present.

TEACHING EXPERIENCE

University of South Alabama  Organic Chemistry Lecture (CH 201 and CH 202; January 1999 - present); Organic Chemistry Laboratory (CH 201L and CH 202L; August 1998 - present); Directed Studies (CH 394 and CH 494; August 1998 - present); Medicinal Chemistry, Special Topics Honors Seminar (CH 490; January 2002 – May 2005); General Chemistry Lecture (CH 131; August 2002 – present); Honors Freshman Experience-H (HON 101; August 2011 – present); Honors Sophomore Experience-H (HON 201; August 2007 – December 2008); Chemistry of Drugs, Special Topics Honors Seminar (CH 490; January 2010 – May 2011).

GRANTS AND RESEARCH SUPPORT (representative)

NSF CHE 0957482, “RUI: Catalysis Using Decarboxylation of Carboxymethylbetaine Functionality”

John Wiley & Sons, “Microscale Organic Laboratory"

NIH NIGMS R15GM085936, “Application of Sulfurane Chemistry in the Assembly of HIV Protease Inhibitors” (priority score 118)

NSF CHE 0806158, supplement to “RUI:  Development of Sulfur Ylide Technology”

Henry Dreyfus Teacher-Scholar Award, “Application of Sulfur Ylide Technology”

NSF CHE 0514004, “Development of Sulfur Ylide Technology”

NSF INT 0405210, “US-UK Cooperative Research:  Decarboxylation of Carboxymethyl Betaines”

NSF CHE 0091795, "Acquisition of Circular Dichroism Spectrometer" (PI Andrzej Wierzbicki)

Merck-AAAS Undergraduate Research Program, "USA Joint Chemistry-Biology Merck-AAAS Undergraduate Research Program" (PI Anne Boettcher (Department of Biology))

ACS-PRF Summer Research Fellowship, "An Approach to the Synthesis of Ingenol and Inenol Analogs"

Cottrell College Science Award, Research Corporation (CC5227), "Chiral 5-Aza-Semicorrins:  New Approaches in Asymmetric Synthesis"

ACS-PRF Type GB Research Grant, "Tandem Cyclization-Cycloadditions in Carbonyl Ylide Formation:  Analyses of Amide, Ester and Urethane Basicity"

PUBLICATIONS

Note: undergraduate research students are underlined for clarity.

S-Ylide Chemistry

Forbes, D. C.; Salter, E. A.; Wierzbicki, A. “Highly Stereoselective S-Ylide Additions onto Chiral Non-Racemic Sulfinyl Imines:  A Computational Study” (submitted)

Forbes, D. C.; Bettigeri, S. V.; Pischek, S. C. “Highly Stereoselective Methylene Transfers onto Butanediacetal-Protected Chiral Non-Racemic Sulfinyl Imines Using S-Ylide Technology,” Chem. Commun. 2009, 1882-1884

Forbes, D. C.; Bettigeri, S. V.; Amin, S. R.; Bean, C. J.; Law, A. M.; Stockman, R. A.; “Synthesis of Chiral Aziridines through Decarboxylative Generation of Sulfur Ylides and their Reaction with Chiral Sulfinyl Imines,” Synthetic Communications 2009, 39, 2405-2422

Forbes, D. C. Bettigeri, S. V.; Al-Azzeh, N. N.; Finnigan, B. P.; Kundukulam, J. A. “Sulfenylation Chemistry using Polymer-Supported Sulfides,” Tetrahedron Letters 2009, 50, 1855-1857

Forbes, D. C.; Bettigeri, S. V.; Patrawala, S. A.; Pischek, S. C.; Standen, M. C. “Methylidene Transfer Agents:  Preparation of Chiral Non-Racemic Carbocycles,” Tetrahedron 2009, 65, 70-76

Forbes, D. C.; Amin, S. R.; Bean, C. J.; Standen, M. C. “Aryl Substituted Sulfonium Betaines:  Preparation and Use in the Epoxidation of Aldehydes,” J. Org. Chem. 2006 71, 8287-8290

Forbes, D. C.; Standen, M. C.; Lewis, D. L. "Sulfur Ylides via Decarboxylation of Carboxymethylsulfonium Betaines: A Novel and Mild Protocol for the Preparation of Oxiranes” Organic Letters 2003 5, 2283-2286

Ionic Liquids Technologies

Forbes, D. C.; Patrawala, S. A.; Tran, K. L. T. “Ionic Liquid Metal-Conjugates:  Formation of an Imidazolium Dirhodium(II) Carboxylate,” Organometallics 2006 25, 2693-2695

Forbes, D. C.; Law, A. M.; Morrison, D. W. “The Knoevenagel Reaction:  Analysis and Recycling of the Ionic Liquid Medium” Tetrahedron Lett. 2006, 47, 1699-1703

Forbes, D. C.; Weaver, K. J. "Brønsted Acidic Ionic Liquids:  Role of Water in the Fischer Esterification of Acetic Acid and Ethanol” J. Molecular Catalysis A:  Chemical 2004. 214, 129-132

Cole, A. C.; Jensen, J. L.; Ntai, I.; Tran, K. L. T.; Weaver, K. J.; Forbes, D. C.; Davis, J. H., Jr  "Novel Brønsted Acidic Ionic Liquids and Their Use as Dual Solvent-Catalysts" J. Am. Chem. Soc. 2002 124, 5962-5963

Morrison, D. W.; Forbes, D. C.; Davis, J. H., Jr. “Base Promoted Reactions in Ionic Liquid Solvents.  The Knoevenagel and Robinson Annulation Reactions” Tetrahedron Lett. 2001, 42, 6053-6055

Diazo Carbonyl Chemistry

Forbes, D. C.; Barrett, E. J.; Lewis, D. L.; Smith, M. C. "A New and Efficient Route Toward the Preparation of Diazo Ketones using Cyanuric Chloride and Diazomethane" Tetrahedron Lett. 2000, 41, 9943-9947

Doyle, M. P.; Ene, D. G.; Forbes, D. C.; Pillow, T. H. " Chemoselectivity and enantiocontrol in catalytic intramolecular metal carbene reactions of diazo acetates linked to reactive functional groups by naphthalene-1,8-dimethanol", Chem. Commun. 1999 1691

Doyle, M. P.; Forbes, D. C.; Xavier, K. R. “Dirhodium(II) Catalyzed Carbonyl Ylide Generation.  Stereoelectronic Control in Dioxolane Formation”, Russ. Chem. Bull. 1998, 47, 932-937

Forbes, D. C.; Ene, D. G.; Doyle, M. P. “Stereoselective Synthesis of Substituted 5-Hydroxy-1,3-dioxanes”, Synthesis 1998, 879-882

Doyle, M. P.; Forbes, D. C.; Vasbinder, M. M.; Peterson, C. S. “Enantiocontrol in the Generation and Diastereoselective Reactions of Oxonium Ylides Catalyzed by Chiral Dirhodium(II) Carboxamidates.  Metal-Stabilized Ylides as Reaction Intermediates”, J. Am. Chem. Soc. 1998, 120, 7653-7654

Doyle, M. P.; Forbes, D. C.; Protopopova, M. N.; Stanley, S. A.; Vasbinder, M. M.; Xavier, K. R. “Stereocontrol in Intermolecular Dirhodium(II) Catalyzed Carbonyl Ylide Formation and Reactions.  Dioxolanes and Dihydrofurans”, J. Org. Chem. 1997, 62, 7210-7215

Doyle, M. P.; Ene, D. G.; Forbes, D. C.; Tedrow, J. S. “Highly Enantioselective Oxonium Ylide Formation and Stevens Rearrangement Catalyzed by Chiral Dirhodium(II) Carboxamidates”, Tetrahedron Lett. 1997, 38, 4367-4370

Buck, R. T.; Doyle, M. P.; Drysdale, M. J.; Ferris, L.; Forbes, D. C.; Haigh, D.; Moody, C. J.; Pearson, N. D.; Zhou, Q.-L. “Asymmetric Rhodium Carbenoid Insertion into the Si-H Bond”, Tetrahedron Lett. 1996, 37, 7631-7634

Chemical Education

Forbes, D. C.; Doyle, M. P. “A Guidance Report for Entering Academics in Organic Chemistry” (submitted)

Forbes, D. C.; Davis, P. M. “Forging Faculty Student Relationships at the College Level Using a Freshman Research Experience“ J. Chem. Ed. 2008, 85, 1696-1698.

Forbes, D. C.; Agarwal, M.; Ciza, J. L.; Landry, H. A. “Zeroing In on Electrophilic Aromatic Substitution” J. Chem. Ed. 2007, 84, 1878-1881

Forbes, D. C. “Incorporation of Medicinal Chemistry into the Organic Chemistry Curriculum” J. Chem. Ed. 2004, 81, 975-976

Reviews/Book Chapters

Doyle, M. P.; Forbes, D. C. “Catalytic Approaches to Ylide Generation and Reactions” In Nitrogen Oxygen and Sulfur Ylides in Synthesis:  A Practical Approach; Clark, J. S., Ed.; Oxford Press:  Oxford, 2002, Chapter 2.3, pp. 141-153

Forbes, D. C.; McMills, M. C. “Catalytic Asymmetric Metal Carbene Transformations” Current Organic Chemistry 2001, 5, 1091-1105

Hodgson, D. M.; Stupple, P. A.; Forbes, D. C. “Reactions Involving Metallocarbenes” In Rodd's Chemistry of Carbon Compounds:  Asymmetric Catalysis; Sainsbury, M., Ed.; Elsevier:  Oxford, 2001, Chapter 3, pp. 65-99.

Doyle, M. P. and Forbes, D. C., "Catalytic Enantioselective Cyclopropanation, Carbon-Hydrogen Insertion, and Ylide Reactions", in Chemistry for the 21st Century: Transition Metal Catalyzed Reactions, S.G. Davies and S. Murahashi, Eds., Blackwell Science Ltd., Oxford, UK, 1999, Chapter 14, pp. 289-301

Doyle, M. P.; Forbes, D. C. “Recent Advances in Asymmetric Catalytic Metal Carbene Transformations”, Chem. Rev. 1998, 98, 911-936

Book

Mayo, D. W.; Pike, R. M.; Forbes, D. C. Microscale Organic Laboratory with Multistep and Multiscale Syntheses, 5th ed., Wiley:  New York, 2011.

Microscale Organic Laboratory Resources

The book companion web site:  www.wiley.com/college/mayo

Mayo, D. W.; Pike, R. M.; Forbes, D. C.; Finnigan, B. P.; Messier, P. M.; Leadbeater, N. E.; McGowan, C. B. Microscale Organic Laboratory:  Instructor’s Manual, 5th ed., Wiley:  New York, 2011.

Mayo, D. W.; Pike, R. M.; Forbes, D. C.; Finnigan, B. P.; Messier, P. M.; Leadbeater, N. E.; McGowan, C. B. Microscale Organic Laboratory with Multistep and Multiscale Syntheses:  Website Reference Discussions, 5th ed., Wiley:  New York, 2011.

PROFESSIONAL ORGANIZATIONS

ACS Organic Chemistry Division, 1999 - present
American Chemical Society, 1989 - present
National Collegiate Honors Council, 2004 - present

http://www.southalabama.edu  

University of South Alabama - Mobile, AL, 36688-0002, (251) 460-6181
Date Last Changed: February 2, 2012
dforbes@jaguar1.usouthal.edu
http://www.southalabama.edu/chemistry/forbes/cv.html

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