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Environmental Health & Safety

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Institutional Biosafety Committee (IBC) members review projects; non-exempt projects are sent to the full IBC for review, comment, and approval.
The project submittal deadline is 5 pm on the first Wednesday of each month. [ IBC Meeting schedules]
Summary of the NIH Guidelines will assist you in determining which category/categories your experiments fall under. 

Type of Work


All experiments involving the use of recombinant DNA (rDNA)

Experiments involving synthetic nucleic acids that 
a) are designed to integrate into DNA,
b) are replication competent or able to replicate in a living cell or
c) code for a vertebrate toxin with an LD50 of <100 nanograms/kilogram body weight.

Word Recombinant/Synthetic Nucleic Acid rDNA       

Experiments involving:
a) BSL-2 or BSL-3 human, animal, or plant pathogens,
b) Unknown human and animal pathogens, 
c) Primary human tumor cells, 
d) Cell lines immortalized with a virus (e.g. EBV, SV40) or
e) Human blood, body fluids, or tissues known to be positive for human
disease-causing agents

Acrobat Biological Agent   Word Biological Agent

Any work with biological toxins with a mammalian LD50 ≤ 100 µg/kg body weight

Acrobat Acute Toxin Updated 08/03/17

Addition or deletion of project personnel or project location; termination of project

Word Administrative Amendment

Change to experimental plan (i.e. addition or deletion of genes, hosts, agents) for any
existing registration.  Note that major changes may require a new registration.

Word   Technical Change Amendment*

*The new use of rDNA in animals or new use of agents which fall under a different section of the NIH Guidelines for Research Involving Recombinant DNA Molecules than the original project approval will need to be reviewed and approved by the Institutional Biosafety Committee (IBC).


Any materials described under the Biological Agent registration that are not currently being used for experiments and are not part of an active registered project (BA or RD), but possessing value either due to their difficulty to obtain or as needed for future projects should be submitted under a Storage Registration. Prior to these materials being used in experiments, they must be appropriately registered on a Biological Agent project.

Word   Biological Agent Storage Registration


Permit Registration

Word Permit Registration Form


Animal Contact Medical Monitoring Program

Acrobat Risk Assessment for Animal Contact 

Acrobat Renewal Risk Assessment for Animal Contact 

Email Completed Risk Assessment Forms to:


Biohazard Decontamination Form

PDF   Biohazard Decontamination Documentation Updated 07/2016


BioPath:  Biohazards Medical Monitoring Program

Acrobat Authorization Form

Acrobat   Medical Assessment Questionnaire


Bloodborne Pathogen Program and
Biomedical Waste Training Compliance

Acrobat Receipt of BBP Materials and Training Coordinator Designation Form   Word Word

Acrobat List of Individuals Trained   Word Word

Acrobat Acceptance/Declination of HBV Vaccination (Training & Vaccination Form)

Acrobat Standard Operating Procedures   Word Word




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