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Home   Programs   Biological Safety   Toxins of Biological Origin Toxin Table

Toxin Table

Toxin

Species

Route

LD50
(µg/kg body weight)

Abrin

Mouse
Human

IV
Ingestion

0.7
5-7

Aerolysin

Mouse

IV

7*

Boutlinum Toxin A

Mouse

IP

0.0012*

Botulinum Toxin B

Mouse

IP

0.0012*

Botulinum Toxin C1

Mouse

IV

0.0011

Botulinum Toxin C2

Mouse

IP

0.0012

Botulinum Toxin D

Mouse

IP

0.0004

Botulinum Toxin E

Mouse

0.0011*

Botulinum Toxin F

Mouse

IV

0.0025

Β-Bungarotoxin

Mouse
Mouse

IP
IV

7.8
10

Caeruleotoxin

Mouse

IV

40

Cereolysin

Mouse

IV

4080

Ciguatoxin 2

Mouse

IP

1

Ciguatoxin 3

Mouse

IP

0.9

Clostridium difficile enterotoxin A

Mouse

IP

0.5

Clostridium perfringens alpha toxin, lecithinase

Mouse

IV

3

Clostridium perfringens theta toxin, perfringolysin O

Mouse

IV

13-16

Clostridium perfringens enterotoxin

Mouse

IV

81

Clostridium perfringens beta-toxin

Mouse
Mouse

IP
IV

4.5
0.31

Clostridium perfringens delta-toxin

Mouse

IV

5*

Clostridium perfringens epsilon-toxin

Mouse

0.1*

Conotoxins

10-100

Crotoxin

Mouse

IV

82

Diacetoxyscirpenol (DAS)#

Dog

IV

1100

Diphtheria toxin

Mouse
Hamster

IV
IP

0.01
6.5

Listeriolysin

Mouse

3-12*

Maitotoxin

Mouse

IP

0.6

Modeccin

Rat

IP

1.3

Nematocyst toxins

Mouse

IV

33-70

Notexin

Mouse

IV

5

Palytoxin

Rat
Mouse

IV
IP

0.089
0.05

Pertussis toxin

Mouse

IP

18

Pneumolysin

Rabbit

IV

1.5

Pseudomonas aeruginosa exotoxin A

Mouse
Mouse

IP
IV

14
3

Ricin

Mouse
Rat

IV
IP

2.2
1.5

Saxitoxin

Mouse

IV

3-9

Scaritoxin

Mouse

IP

50

Shiga toxin

Mouse
Rabbit

IP
IV

0.25
0.0022

Shigella dysenteriae neurotoxin

Mouse
Mouse

IP
IV

1.3
0.45

Streptolysin O

Mouse

IV

8

Streptolysin S

Mouse

IV

25

Staphylococcus aureus alpha toxin

Mouse

IV

0.04-0.06

Staphylococcus aureus enterotoxin B

Monkey

IV

20

Staphylococcus aureus enterotoxin F

Rabbit
Rabbit

SubQ
IV

2
10

T-2 toxin#

Pig

IV

1000

Taipoxin

Mouse

IV

2

Tetanus toxin

Mouse

SubQ

0.003

Tetrodotoxin

Mouse

IV/IP

8

Viscumin

Mouse

IV

2.4

Volkensin

Mouse

IP

1.38

Yersinia pestis murine toxin

Mouse

IV

10

IV = intravenous; IP = intraperitoneal; SubQ = subcutaneous
Toxins in bold are Select Agent toxins.
#Although DAS and T-2 toxins have LD50 values > 100µg/kg body weight, they must be registered as Acute Toxins with the Biosafety Office due to the fact that they are Select Agent toxins.
*MLD = minimum lethal dose; lowest dose reported to kill at least one subject

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