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January, 2012 Events

Tues, Jan 17  VIP Campus Hike for HBOI/FAU Friends & Their Guests:  Meet at the Ocean Discovery Center at 9:00 a.m. then walk to Harbor Branch’s Link Port Café for breakfast (cash only).  On this 2 ½ mile hike of Harbor Branch you will look for manatees, alligators, dolphins and other wildlife.  You will also get a peek inside the new buildings along the way. Reservations required. Free to members and their guests.

Wed, Jan 18  Ocean Science Lecture Series: “Ocean Renewable Energy: Harnessing the Power of the Sea” Sue Skemp, Southeast National Marine Renewable Energy Center, FAU   FAU is building the capability, infrastructure, expertise, and partnerships needed to develop the methodology and tools to deploy, test, and validate commercially-viable ocean energy systems, such as harnessing the power of the Gulf Stream for generating electricity.  Learn how this research is making a unique contribution to a broadly diversified portfolio of renewable energy for the nation’s future.4 p.m. and 7 p.m. – Johnson Education Center – Free Admission

Thurs, Jan 19 Tour of Adams Ranch:  Come experience this family ranch founded in 1937 and learn what cattle raising is all about.  Ride over 65,000 acres of beautiful range land that is home to a variety of wildlife.  Gather back at the ranch for a tasty barbeque of chicken and ribs with all the trimmings. Reservations required. Cost members $25 pp; non-members $30 pp. 9:45 a.m. – 3:00 p.m.

Wed, Jan 25              Behind the Scenes Tour of Florida Oceanographic Society:  See areas of this marine nature center that the general public doesn’t get to see. Then enjoy the wonders of the 750,000 gallon Game Fish Lagoon with 35 different species of aquatic animals which include sea turtles, tropical and game fish and an 8 ft. shark.  Nature trails provide the opportunity to spot wildlife along the coastal hardwood hammocks and mangrove swamp communities and don’t miss the Frances Langford Visitors Center.         Reservations required. Cost $18 pp. 10:00 a.m. -  3:00 p.m.

Wed, Jan 25              Ocean Science Lecture Series: “Understanding the Planetary Life Support System: Next Generation Science in the Ocean Basins” John Delaney, University of Washington The global ocean ecosystem is essential to the quality of life on the continents.  The oceans are very complicated, changing rapidly and unpredictably.  Sophisticated computational simulations and models of oceanic behavior require immense amounts of carefully crafted data input to become predictive.  Novel approaches to working the oceans in the coming generations have the potential to revolutionize our perceptions (and eventual management) of our entire planet. 4 p.m. and 7 p.m. – Johnson Education Center – Free Admission

Tues, Jan 31  VIP Tour for HBOI/FAU Friends & Their Guests:  Tour begins at 9:30 a.m. at the Ocean Discovery Center.  Reservations required. 

February Events

Wed, Feb 1 OSLS: "Saving the Gentle Giants" - Manatee Protection Sensors for Flood Control Gates and Navigation Locks  Larry Taylor, HBOI/FAU – Engineers at Harbor Branch have developed two unique sensor systems that prevent manatees from being injured in flood control gates and navigation locks. Join Larry Taylor, Project Manager for the Manatee Protection Systems Program since 1997, as he describes these innovative solutions and the successful installations at 18 flood gates and 8 boat locks.

The winter lecture series is presented every Wednesday (January 12 – March 21) at 4:00 p.m. and 7:00 p.m. An opportunity to meet the speaker, appetizer buffet and cash bar follow the presentation. The lectures are open to the public, free of charge and reservations are not required. For more information please call (772) 242-2506.

Wed, Feb 8 OSLS: “Seagrass Monitoring in the Indian River Lagoon – No Such Thing as Status Quo” – Lori Morris, St. Johns River Water Management District – Positive trends in IRL seagrass coverage has been the story over the past 17 years. However, what appeared to be a functioning, balanced estuary has recently tipped into a spiraling decline. Can the balance be restored?

The winter lecture series is presented every Wednesday (January 12 – March 21) at 4:00 p.m. and 7:00 p.m. An opportunity to meet the speaker, appetizer buffet and cash bar follow the presentation. The lectures are open to the public, free of charge and reservations are not required. For more information please call (772) 242-2506.

Feb 9 –  Indian River Lagoon Symposium –8 a.m. - 5:30 p.m.agencies and public are invited to register to attend; $20 for professionals, $10 other/public due by Jan 31.  Late registration $25 pp and $15 for day of meeting registration.   Registration includes coffee breaks, lunch and reception.  For more information: www.indianriverlagoon.org.

Feb. 10 –  “Love Your Lagoon” Dinner – 6 - 10 p.m. Ticketed event.  $125 pp and up for higher sponsorship levels – for tickets call 466-9876 ext 221, rsvp@hboifoundation.org or purchase tickets online at www.indianriverlagoon.org.  Proceeds will support the annual Indian River Lagoon Symposium and research on the IR Lagoon at HBOI.

Mon, Feb 13 VIP Naturalists’ Walking Tour for HBOI/FAU Friends and their Guests: Meet at the Ocean Discovery Center at 9:30 a. m. before heading on campus to the Harbor Branch Café and a quick breakfast with ODC guide Sunny Gardner and a Harbor Branch naturalist. Bring your cameras and field glasses, as we will meander through some of the more natural areas of campus looking for birds, bugs, manatees, alligators, dolphins and other wildlife. Reservations required. Call (772) 242-2559. Free to members and their guests.

Wed, Feb 15 OSLS: “Undersea Gliding in the Gulf” Harbor Branch’s Latest Winged Robots’ Recent Mission to Explore Gulf of Mexico Waters Fraser Dalgleish, HBOI/FAU – As part of the Florida Shelf Edge Exploration (FLOSEEII) cruise, two Spray gliders operated by Harbor Branch’s Ocean Visibility and Optics Lab in collaboration with Bluefin Robotics were deployed for several months at Pulley Ridge. These glider deployments allowed large scale measurement of water quality parameters above the coral reef and the surrounding waters in support of cruise objectives.

The winter lecture series is presented every Wednesday (January 12 – March 21) at 4:00 p.m. and 7:00 p.m. An opportunity to meet the speaker, appetizer buffet and cash bar follow the presentation. The lectures are open to the public, free of charge and reservations are not required. For more information please call (772) 242-2506.

Wed, Feb 22 Eco-Boat Trip – departs from Harbor Branch. A special look at land birds in the native scape near campus and shore birds on the Lagoon, it’s Birding 101 with Capt. Chop Lege and his knowledgeable crew. Join Friends for a short walk on campus and a trip aboard the pontoon boat “Gator” to see birds, dolphins, turtle, manatees and more. Departing 10:30 a.m. and returning in time for lunch from the Harbor Branch Café. $50pp. Reservations required. Call (772) 242-2559.

Wednesday, Feb 22   OSLS: There is no lecture this week.

Tue, Feb 28 Sunset Cruise up the North Fork of the St. Lucie River. Depart downtown Stuart from Sailor’s Return at 3:30 p.m. for a trip with Capt. Nancy up the North Fork and to some great areas for target birds. Return to dock in time to enjoy supper downtown. Reservations required. $40pp. Call (772) 242-2559 for directions and reservations.

Wed, Feb 29 OSLS: “Challenges Facing Marine Mammals in a Changing Arctic” Greg O’Corry-Crowe, HBOI/FAU – Harbor Branch’s Polar Research Program uses molecular genetic techniques and satellite-linked telemetry in the study of northern temperate, Arctic and Antarctic marine mammals. Join Dr. O’Corry-Crowe as he describes the range of modern field and lab techniques used by his program to investigate the effects of climate change and ecosystem regime shifts on marine mammals and other apex predators in the Artic.

The winter lecture series is presented every Wednesday (January 12 – March 21) at 4:00 p.m. and 7:00 p.m. An opportunity to meet the speaker, appetizer buffet and cash bar follow the presentation. The lectures are open to the public, free of charge and reservations are not required. For more information please call (772) 242-2506.

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Esther A. Guzmán, Ph.D.
Assistant Research Professor
HBOI Image

eguzman9@hboi.fau.edu
772-242-2452

Education

2004, Ph.D. Immunology,
University of Texas MD Anderson Cancer Center, Houston, Texas.

1996, B.S. Molecular Biology/Biotechnology,
Salem-Teikyo University, Salem, West Virginia.

Career

1993 Student Fellow; Howard Hughes Medical Institute Summer Fellowship; West Virginia University, Morgantown, West Virginia

1995-1996 Independent Researcher, Salem-Teikyo University, Salem, West Virginia

1996-1997 Graduate Research Assistant, Theoretical Biology and Biophysics Division; HIV Database, Los Alamos National Laboratory, Los Alamos, New Mexico

1997-2001 Graduate Research Assistant, University of Texas M.D. Anderson Cancer Center, Houston, Texas

2001-2004 Graduate Research Assistant, University of California, Riverside, California

2004- 2005 Postdoctoral Fellow, Henry Ford Health System, Detroit, Michigan

2005-2007 Postdoctoral Investigator, Harbor Branch Oceanographic Institution, Ft.Pierce, Florida

2007 Assistant Research Scientist, Harbor Branch Oceanographic Institution, Ft. Pierce, Florida

2008-present Assistant Research Professor Harbor Branch Oceanographic Institute at FAU

Detailed CV

Research Interests

Dr. Guzmán joined the drug discovery program at Harbor Branch in 2005 as a Postdoctoral Investigator where she has performed research aimed at the discovery of novel cancer therapeutics including both development of novel molecular target based assays and determination of the mechanism of action of compounds discovered at HBOI. In 2007, Dr. Guzmán became the leader of the cell biology program at the Center for Marine Biomedical and Biotechnology Research at HBOI. This program focuses on drug discovery for pancreatic cancer. New focuses will target cancer stem cells in pancreatic, breast and other cancers, as well as components of the immune system that are abnormal in most cancers. Her work at Harbor Branch has resulted in the discovery of novel anti-metastatic properties for manzamine A; the inhibition of topoisomerase II by isobatzelline E; the activation of Chk1/2 kinase and subsequent block of cell proliferation by aphrocallistin and the development of assays to detect compounds that target the MAP kinase pathway, GSK3β, NFKB, and survivin. This work has resulted in the filing of two provisional patents, a peer reviewed publication and three manuscripts currently in preparation.

Last Modified 10/14/11

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