FIRST ANNUAL NSF-FUNDED SHORT COURSE ON STATISTICAL GENETICS & STATISTICAL GENOMICS

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Held On:    Mon 7/21/2008 - Fri 7/25/2008     
Location:    Doubletree Hotel Birmingham
Heritage 2 Meeting Room
808 South 20th Street
Birmingham, AL 35205
(205) 933-9000; fax (205) 933-0920
When making your reservation, please identify yourself as with the "Statistical Genetics short course" group to receive the reduced room rate.

Overview:

Focusing on the analysis of complex traits characterized by quantitative variation, this five-day course will offer an interactive program to enhance researchers' ability to understand & use statistical genetic methods, as well as implement & interpret sophisticated genetic analyses. Including hands-on computer demonstrations and practice, the course will be useful to a wide range of investigators studying the genetics of plants, model organisms, livestock, wildlife, and humans, helping investigators to better understand, use, and, in some cases even undertake research on, statistical genetic methods. Statistical genetic methodology is critical to advancing basic biology which is, in turn, critical to fields like genetic epidemiology, evolutionary biology, ecology, pest management, marine biology, medicine, forestry, and agriculture.

Schedule of Events: Agenda

**NOTE: You will need RealPlayer to view videos.

DATE    TIME    TOPIC    SPEAKER    Resource(s)   
Mon
7/21/2008    8:00 - 9:00 am    Registration       
9:00 - 9:15 am    Introductory Remarks    Hemant K. Tiwari, Ph.D.     
9:15 - 10:00 am    Discussion:  Interests & Expectations    Participants     
10:00 -10:15 am    Break       
10:15 - 12:00 pm    Introduction to Biostatistics    Warren Ewens, Ph.D.    Notes, Slides
Video    
10:15 - 12:00 pm    Introduction to Genetics & Genomics    Robert Elston, Ph.D.    Video    
12:00 - 1:30 pm    Lunch       
1:30- 2:00 pm    Case Control and Association Testing    David B. Allison, Ph.D.    Video    
2:00- 3:15 pm    The qualitative and the quantitative TDT (Transmission - Disequilibrium Test)    Warren Ewens, Ph.D.    Notes, Slides
Video    
3:15 - 3:30 pm    Break       
3:30 - 4:15 pm    Structured Association Testing (SAT)    David B. Allison, Ph.D.    Video    
4:15 - 5:00 pm    Discussion    All Faculty     
DATE    TIME    TOPIC    SPEAKER    Resource(s)   
Tue
7/22/2008    8:00 - 9:00 am    PLINK Tutorial    Hemant K. Tiwari, Ph.D.    Video    
9:00 - 9:15 am    Break       
9:15 - 10:30 am    Haplotype Analysis in Association Studies    Kui Zhang, Ph.D.    Video    
10:30 - 11:45 am    Design of Microarray Experiments    Guilherme Rosa, Ph.D    Video    
11:45 - 1:15 pm    Lunch       
1:15 -2:30 pm    Microarray: array types, quality control, and systems biology    Grier Page, Ph.D.    Video    
2:30 - 2:45 pm    Break       
2:45 - 4:00 pm    Microarray Analysis: Inference    Sandra Rodriquez-Zas, Ph.D.    Video    
4:00 - 5:15 pm    Basic Experimental Cross QTL analysis    Xiangqin Cui, Ph.D.    Video    
5:15 - 5:45 pm    Discussion    All Faculty     
DATE    TIME    TOPIC    SPEAKER    Resource(s)   
Wed
7/23/2008    8:00 - 9:00 am    Bioconductor    Xiangqin Cui, Ph.D.    Video    
9:00 - 9:15 am    Break       
9:15 - 10:30 am    Bayesian Interval Mapping    Brian Yandell, Ph.D.    Video    
10:30 - 11:45 am    Bayesian Hierarchical Generalized Linear Models for QTL Analysis    Nengjun Yi, Ph.D.    Video    
11:45 - 1:15 pm    Lunch       
1:15 -2:30 pm    Multivariate trait selection and estimation of multivariate fitness functions    Bruce Walsh, Ph.D.    Video    
2:30 - 2:45 pm    Break       
2:45 - 4:00 pm    Whole Genome Enabled Marker Assisted Selection    Guilherme Rosa, Ph.D.    Video    
4:00 - 5:15 pm    Detecting selection using molecular signature -- Intra-specific approach    Yunxin Fu, Ph.D.    Video    
5:15 - 5:45 pm    Discussion    All Faculty     
DATE    TIME    TOPIC    SPEAKER    Resource(s)   
Thu
7/24/2008    8:00 - 9:00 am    Software Demonstration (HDBSTAT, Power Atlas - Genomics Microarray)    Jelai Wang    Video    
9:00 - 9:15 am    Break       
9:15 - 10:30 am    Methods, Examples, and Implications of Integrative Biology    Atul Butte, Ph.D.    Video    
10:30 - 11:45 am    Genome-Wide Association, Copy Number Variation and Biological Pathway Analysis    Carl Langefeld, Ph.D.    Video    
11:45 - 1:15 pm    Lunch       
1:15 -2:00 pm    Discussion    All Faculty     
3:00 - 6:00 pm    R/qtlbim Software Demo    Brian S. Yandell, PhD    Video    
Bayesian QTL mapping without tears    Nengjun Yi, PhD    Video    
Software Demonstration: HAPLOVIEW and HAPLORE    Kui Zhang, PhD    Video    
JMP Genomics    Amit Patki    Video    
Ingenuity Systems Pathway Analysis (IPA)    Kelly Vaughan, Ph.D.    Video    
6:00 - 7:00 pm    Dinner       
7:00 - 9:00 pm    Hands-on    Faculty (Hemant K. Tiwari, Ph.D.)     
DATE    TIME    TOPIC    SPEAKER    Resource(s)   
Fri
7/25/08    9:00 - 12:00 pm    Roundtable Discussion    Faculty (David B. Allison, Ph.D.)     

Software Hands-On: Participants Pre-read
To insure the depth and practicality of the training program, we will provide 10 laptops to students or student pairs in the classroom. Each computer will be loaded with statistical software including but not limited to SAGE, Mx, Genehunter, Genomic Control programs, STRUCTURE, Ancestry Map, SIMWALK, MERLIN, QTL Express, R/QTL, BQTL, Dandelion, HDBSTAT!, Bioconductor Suite, Phase and Arlequin (all freely available) as well as S-Plus, SPSS and SAS. Many of the faculty have substantial expertise with the use of software for statistical genetics and have even authored some. Please feel invited to bring your own laptop.

UAB Faculty:

External Faculty:

Full List of External Rotating Faculty can be found by Click here.

Contact Information:

Logistics: Richard Sarver
Department of Biostatistics
1665 University Blvd, RPHB 414
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 975-9169
Email: rsarver@uab.edu

Scientific: Hemant K Tiwari, PhD
Department of Biostatistics
1665 University Blvd, 420B
University of Alabama at Birmingham
Birmingham, AL 35294-0022
Phone: (205) 934-4907
Email: HTiwari@ms.soph.uab.edu

Funded by: National Science Foundation

Sponsors: SSG

Contributor: Genome Explorations

NSF Disclaimer:
This material is based upon work supported by the National Science Foundation under Grant No. (NSF MCB-0650606).
Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.

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