Mentor's Bio:
Dipl. Chemical Engineering, Aristotle University of Thessaloniki, Greece, 1987 PhD Chemical Engineering, University of Delaware, 1993 Postdoctoral, Harvard University, 1993-1998

Research Topic(s) Summary:
Theoretical and Computational Biophysics; Protein Folding, Molecular Recognition, Thermodynamics of Biological processes.

Description of Research:

My research is in the area of Theoretical and Computational Biophysical Chemistry, which aims to understand how biological systems work in terms of the fundamental laws of Physics and Chemistry. Biomolecules, such as proteins and nucleic acids, have well defined conformations which often change in the course of their function. Our goal is to understand the forces that operate within and between biomolecules and develop quantitative mathematical models for their energy as a function of conformation. Such models are useful in many ways, such as predicting the three-dimensional structure from sequence, characterizing conformational changes involved in biological function, or predicting the binding affinity between two biomolecules.

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