Carol Moore, Ph.D.

Medical Professor
Microbiology and Immunology

School of Biomedical Education

Office: H-210
Phone: (212) 650-6926
Fax: (212) 650-7583
E-mail: moore@med.cuny.edu

Education

B.S., 1965, Ohio State University;
M.S., 1969, Ph.D., 1970, Pennsylvania State University.

Research Interests

• Using a yeast model for studying human disease mechanisms.

• DNA repair mechanisms and their relationship to human diseases.

• Genetic control of cellular responses to ionizing radiation and radiomimetic anticancer drugs.

• Targeting AIDS fungal pathogens by mutant approaches.

Publications

• Ovalle, R., S.T. Lim, B. Holder, C.K. Jue, C.W. Moore, and P.N. Lipke 1998. A spheroplast rate assay for determination of cell wall integrity in yeast. Yeast 14:1159-1166.
• Moore, C.W. 1999. Bleomycin. pp. 292-297 In: Encyclopedia of Molecular Biology, John Wiley and Sons, New York.
• Moore, C. W., J. Mc.Koy, M. Dardalhon, D. Davermann, M. Martinez, and D. Averbeck 2000. DNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae. Genetics 154:1085-1099.
• Febres, D. E., A. Pramanik, M. Caton, K. Doherty, J. Mc.Koy, E. Garcia, W. Alejo, and C. W. Moore. 2001. The novel BLM3 gene encodes a protein that protects against lethal effects of oxidative damage. Cellular and Molecular Biology 47:1149-1162.
• Davermann, D., M. Martinez, N. Patel, J. McKoy, D. Averbeck, and C. W. Moore, 2002. Impaired mitochondrial function protects against free radical-mediated cell death. Free Radical Biology and Medicine33:1209-1220.
• Anyatonwu, G., E. Garcia, A. Pramanik, M. Powell, and C. W. Moore. 2003. Meiotic and mitotic phenotypes conferred by the blm1-1 mutationand MSH4 suppression in Saccharomyces cerevisiae. International Journal of Molecular Sciences, 4:1-12.
• Moore, C.W., J. McKoy, R. Del Valle, D. Armstrong, E. M. Bernard, N. Katz, and R. E. Gordon, 2003. Fungal cell wall septation and cytokinesis are inhibited by bleomycins. Antimicrobial Agents and Chemotherapy 47:3281-3289.
• Martinez, M., A. Pramanik, S. M. Ndje, C. W. Moore. 2003. Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage. Cellular and Molecular Biology 49:1025-1035.
• Martinez, M., A. Pramanik, J. McKoy, K. Robert, C. W. Moore. 2003. Pleiotrophic cellular deficiencies conferred by the blm5-1 mutation of Saccharomyces cerevisiae. Cellular and Molecular Biology 49:1049-1056.
• Doherty, K., A. Pramanik, L. Pride, J. Lukose, and C.W. Moore. 2004. Expression of the expanded YFL007w ORF and assignment of the gene name BLM10. Yeast 21:1021-1023.

Last Updated: 9/10/10