John Martin, Ph.D.

Medical Professor
Physiology and Pharmacology

Education

B.A., 1973, University of Rhode Island
Ph.D., 1978, Columbia University

Research Interests

• Development of the motor systems of the brain and spinal cord
• Development of motor behavior
• Repair of the damaged motor systems
• Promoting axon regeneration after brain and spinal cord injuries
• Movement control

Publications

Selected recent articles

• Chakrabarty S, Shulman, B, Martin JH. Activity-dependent co-development of the corticospinal system and target interneurons in the cervical spinal cord. J Neurosci. (2009) 29:8816-8827.
• Brus-Ramer M, Carmel, JB, Martin JH. Motor cortex bilateral motor representation depends on subcortical and interhemispheric interactions. J. Neurosci (2009) 29:6196-6206.
• Chakrabarty S, Friel K, Martin JH. Activity-dependent plasticity of the M1 motor map and corticospinal tract connectivity. J. Neurophysiology (2009) 101:1203-1293.
• Salimi I, Friel K, Martin JH. Pyramidal tract stimulation restores normal corticospinal tract connections and visuomotor skill after early postnatal motor cortex activity blockade. J Neurosci (2008) 28:7426-7434.
• Campos L, Chakrabarty S, Haque R, Martin JH. Regenerating Motor Bridge Axons Refine Connections and Synapse on Lumbar Motoneurons to Bypass Chronic Spinal Cord Injury. J. Comp. Neurology (2008) 506:838-850.
• • Related web piece: http://www.newscientist.com/article/mg19726424.900-nerve-bridge-bypasses-spinal-cord-injury.html
  • Related web piece: www.sciencentral.com/articles/view.php3?language=english&type=24119&article_id=218392234&cat=1_4
• Brus M, Carmel JB, Chakrabarty S, Martin JH. Electrical Stimulation of Spared Corticospinal Axons Augments Connections with Ipsilateral Spinal Motor Circuits After Injury. J. Neuroscience (2007) 27:13793-13801.
• Friel K, Martin JH. Rebalancing corticospinal activity promotes recovery of motor skill and anatomical integrity after inactivation during a critical period. J. Neuroscience (2007) 27:11083-11090.
• Beg AA, Sommer JE, Martin JH, Scheiffele P. Alpha2-chimaerin is an essential EphA4 adapter in the assembly of neuronal locomotor circuits. Neuron (2007) 55:768-778.
• Courtine G, Bunge MB, Fawcett JW, Grossman RG, Kaas JH, Lemon R, Maier I, Martin J, Nudo RJ, Ramon-Cueto A, Rouiller EM, Schnell L, Wannier T, Schwab ME, Edgerton VR. Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? Nat Med (2007) 13:561-566.
• Friel K, Drew T, Martin JH. Differential activity-dependent development of corticospinal control of movement and final limb position during visually-guided locomotion. J. Neurophysiol. (2007) 97:3396-3406.

Textbook, book chapters, and review articles

• Martin, JH  Neuroanatomy:  Text and Atlas, 3rd ed. McGraw-Hill, NY  (2003).
• Campos LC, Ambron RT, Martin JH Bridge over troubled waters. NeuroReport 15:2691-2694, 2004
• Martin JH Corticospinal system: from development to motor control. The Neuroscientist 11:161-173, 2005.
• Martin JH Development of the Corticospinal Systems and Spinal Motor Circuits. In: Handbook of Clinical Neurology (3^rd edition). (Eds) A. Eisen and P. Shaw. Elsevier. 2007.
• Martin JH, Friel K, Salimi I, Chakrabarty S. Corticospinal Development. In: Encyclopedia of Neuroscience, volume 3, pp. 302-214. (Ed) L. Squire. Oxford: Academic Press. (2009).
• Martin JH, Friel K, Salimi I, Chakrabarty S. Corticospinal Development. In: Developmental Neurobiology. (Ed) G. Lemke. Amsterdam: Elsevier. (2009).

Last Updated: 3/15/10